Hypocalcemia (Low Calcium Levels)
Hypocalcemia occurs when blood calcium levels fall below normal. Causes include:
Vitamin D Deficiency: Reduces calcium absorption from the intestine, leading to low blood calcium.
Hypoparathyroidism: Underactive parathyroid glands lead to reduced parathyroid hormone (PTH) production, essential for calcium regulation.
Kidney Disease: Impairs the body’s ability to maintain calcium and phosphorus balance.
Medications: Certain drugs can interfere with calcium absorption or excretion.
Symptoms often include muscle spasms or cramping, numbness or tingling in the extremities, and, in severe cases, cardiac arrhythmias or seizures. Treatment generally involves calcium supplements, possibly along with vitamin D, and addressing the underlying cause.
Hypercalcemia (High Calcium Levels)
Hypercalcemia is characterized by abnormally high levels of calcium in the blood. It can be caused by:
Hyperparathyroidism: Overactive parathyroid glands produce too much PTH, leading to increased calcium.
Cancers: Certain cancers, like lung or breast cancer, can raise blood calcium levels.
Prolonged Immobilization: Can cause calcium to leach out of bones into the bloodstream.
Medications: Some drugs, including diuretics and lithium, can increase calcium levels.
Symptoms may range from mild, such as fatigue and weakness, to severe, including kidney stones, bone pain, and neurological disturbances. Treatment is focused on the underlying cause and may include hydration, medications to lower calcium levels, and dietary modifications.
Hypoparathyroidism
This rare condition involves inadequate production of PTH, leading to low calcium and high phosphorus levels. It can occur post-surgically, particularly after thyroid or neck surgery, or due to autoimmune diseases or genetic factors.
Symptoms include muscle cramps, tingling, and seizures.
Treatment typically involves long-term calcium and vitamin D supplementation to maintain normal blood calcium levels.
Hyperparathyroidism
Hyperparathyroidism results from excessive PTH production, usually due to a benign tumor on a parathyroid gland. It leads to high calcium levels, causing symptoms like bone pain, kidney stones, fatigue, and depression.
Treatment options include surgical removal of the overactive gland, medications to manage symptoms, and careful monitoring of calcium levels.
Vitamin D Deficiency
Vitamin D is vital for calcium absorption and bone health. Deficiency can result from limited sun exposure, poor diet, or absorption disorders. It leads to weak bones, muscle weakness, and in children, can cause rickets.
Treatment involves vitamin D supplementation and increased exposure to sunlight, along with dietary changes to ensure adequate vitamin D intake.